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Copyright @ Pol J Cosmetol
Pol J Cosmetol 2017, 20(2): 111-115pl  Chromium and skin - allergic reactionsJacek Arct, Dorota Kulik, Katarzyna Pytkowska Wyższa Szkoła Zawodowa Kosmetyki i Pielęgnacji Zdrowia w Warszawie Summary Chromium salts, the metal itself and its alloys are potent allergens and common cause of contact dermatitis. It was found that the toxicity have ions of trivalent chromium Cr+++. This form of chromium barely penetrates the skin barrier as opposed to an easily accessible via the contact hexavalent chromium (chromate and dichromates). This last in the body is reduced to toxic Cr+++. Chromium allergy, because of distribution of this metal, is considered a severe disease. The most common are allergy types V and VI. One method to avoid sensitization to chromium is the use of appropriate cosmetics impeding the penetration of ions of the metal through the epidermal barrier. In studies provided in model lipid membranes in the side by side chambers it was found, that among the popular cosmetic ingredients, the best results gives the use of lactic acid. Key words: allergy, chromium, contact dermatitis, topical bioavailability, skin, hapten, lactic acid |