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Pol J Cosmetol 2015, 18(3): 191-196pl  Selected active substances in mesotherapy treatmentsMonika Morąg, Marzena Glinka, Iwona Jokiel Społeczna Akademia Nauk w Łodzi Summary In order to maintain the normal structure and function of the skin as long as possible, a variety of beauty treatments is used. One of them is mesotherapy treatment (intradermotherapy), which has been successfully used for many years both in aesthetic dermatology and cosmetology. It is used in the prevention of aging and biorevitalisation of the skin, reduction of cellulite and adipose tissue, treatment of scars and stretch marks, as well as the prevention of hair loss and stimulation of hair growth. Depending on therapeutic recommendations and patient´s individual needs, taking into account the area of the body where treatment is to be performed, various active ingredients are used. They are used individually or in the form of mixtures, so-called "cocktails". Due to their biological effect, they may, among others, stimulate the activity of fibroblasts and the synthesis of collagen, inhibit or enhance the activity of proteolytic and lipolytic enzymes, stimulate the production of extracellular matrix components and structural elements of the cells, eliminate the excess of reactive oxygen forms, as well as improve the microcirculation. For mesotherapy there are used, among others, biotin, DMAE (dimethylaminoethanol), phosphatidylcholine, caffeine, organic silica, ascorbic acid, hyaluronic acid, L-carnitine, sodium pyruvate, polideoxyribonucleotides and plant extracts, such as globe artichoke leaf extract, yellow sweet clover herb extract and cestella asiatica herb extract. Key words: mesotherapy, active substances, fibroblasts, collagen, rejuvenation, adipose tissue |