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Pol J Cosmetol 2011, 14(2): 99-106pl  Chemical peels application in removal of solar hyperpigmentation on face skinMonika Migdalska-Sęk 1/, Dorota Pastuszak-Lewandoska 1/, Zuzanna Janus 1/, Janina Grzegorczyk 2/, Ewa Brzeziańska 1/ 1/ Zakład Molekularnych Podstaw Medycyny Uniwersytetu Medycznego w Łodzi 2/ Zakład Mikrobiologii i Laboratoryjnej Immunologii Medycznej Uniwersytetu Medycznego w Łodzi Summary Introduction. Hyperpigmentation may be caused by internal and external causes, and the major external cause is sun exposure. This darkening effect occurs due to the skin´s natural protection against the sun, i.e. production of melanin in skin cells called melanocytes located in the deeper layers of the epidermis. Hyperpigmentation treatments are available to get rid of brown spots. Aim. The aim of the study was the assessment of efficacy of two chemical peels: TCA and Salipeel plus. The efficacy of the used peels was compared, regarding the grade of removal of sun spots located on different parts of face. Material and methods. 60 women were included in the study, at the age between 20 and 60. They were divided into 2 equal groups treated with one of two chemical peels: TCA or Salipeel Plus. Additionally, a questionnaire was designed, composed of questions concerning, among others, the habits of the patients connected with the frequency of tanning (outdoor and indoor), use of cream with sunscreen, the knowledge on sun spots occurrence and factors influencing the hyperpigmentation. Results. High efficacy of TCA was demonstrated, especially on cheeks and forehead. Sun spots became significantly lighter, the color and state of skin face was improved. No adverse effects were observed. Salipeel Plus showed a little bit smaller depigmentation effects. Both applied peels appeared to be more effective in case of women who were using lightening face creams during the treatment (p<0.05, t-Student test). Conclusions. Both applied peels are effective and recommended for removal of hyperpigmentation spots. Key words: UVA/UVB radiation, melanogenesis, solar hyperpigmentation, TCA peeling, Salipeel plus |