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Copyright @ Pol J Cosmetol
Pol J Cosmetol 2009, 12(4): 228-237pl,en  Role of metalloproteinases in cosmetologyMarta Michalska 1/, Łukasz Glinka 2/, Aleksandra Palatyńska-Ulatowska 3/ 1/ Zakład Biochemii Farmaceutycznej Katedry Chemii Farmaceutycznej i Biochemii Uniwersytetu Medycznego w Łodzi 2/ Zakład Chemii Bionieorganicznej Katedra Chemii Medycznej Uniwersytetu Medycznego w Łodzi 3/ Zakład Endodoncji Uniwersytetu Medycznego w Łodzi Summary Metaloproteinases are extracellular or membrane, metal-dependant protein hydrolases. Metaloproteinases constitute zinc- or calcium-dependant endopeptidases. In phisiological or pathological conditions it catalyse many ractions concerning vital processes of any tissue or organ. Increased activity of these enzymes was stated in malignancies, metastases, cardiac diseases and many skin illnesses. In response to modern trends in cosmetology numerous research has been done on introduction of metaloproteinases inhibitors to cometic preparations "intelligent cosmetics", which could prevent collagene degradation as well as skin aging. Key words: metaloproteinases, metalloproteinases inhibitors, collagen degradation |