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Pol J Cosmetol 2023, 26(2): 78-82pl  Multidirectional effect of azelaic acid on the skinNatalia Hojda 1/, Kamila Michalak 2/, Małgorzata Czerny 2/, Paulina Budzanowska 2/ 1/ Koło Naukowe Wyższej Szkoły Fizjoterapii z siedzibą we Wrocławiu 2/ Wyższa Szkoła Fizjoterapii z siedzibą we Wrocławiu Summary More and more people are turning to cosmetology practices for help with various skin conditions. Problems with acne vulgaris, rosacea or hyperpigmentation are very common. The severity of the diseases can depend on many factors, both endogenous and exogenous. In many cases, a great choice of treatment therapy will be the use of chemical peels. Such a multidirectional effect is demonstrated by azelaic acid. As a tyrosinase inhibitor, it has an inhibitory effect on melanogenesis and has a brightening effect. In turn, in the context of acne vulgaris and rosacea, it inhibits the development of inflammation and neutralizes the inflammation already present. The anti-inflammatory action is a very valuable property in the pathogenesis of both types of acne. Azelaic acid is a low-irritant acid and is therefore also suitable for sensitive skins. It is also used in combination therapies and the cosmetologist´s experience and knowledge will allow it to be appropriately matches to the skin. Key words: chemical peelings, azelaic acid, acne vulgaris, hyperpigmentation, rosacea, melanogenesis, tyrosinase |